Carbohydrate Drug Design by Anatole A. Klyosov, Zbigniew J. Witczak, and David Platt

By Anatole A. Klyosov, Zbigniew J. Witczak, and David Platt (Eds.)

content material: evaluate. Carbohydrates and drug layout: what's new during this e-book / Anatole A. Klyosov --
Carbohydrate therapeutics: new advancements and techniques / Zbigniew J. Witczak --
melanoma. improvement of a polysaccharide as a car to enhance the efficacy of chemotherapeutics / David Platt, Anatole A. Klyosov, and Eliezer Zomer --
DAVANAT and colon melanoma: preclinical and scientific (phase I) reviews / Anatole A. Klyosov, Eliezer Zomer, and David Platt --
Synthesis and organic task of doxo-galactose and doxo-galactomannan, new conjugates of doxorubicin with D-galactose and 1,4, [beta]-D-galactomannan / Anatole A. Klyosov ... [et al.] --
Human immunodeficiency virus. Carbohydrate-based vaccines opposed to HIV/Aids / Lai-Xi Wang --
towards a carbohydrate-based HIV-1 vaccine / Daniel Calarese ... [et al.] --
Pathogen administration. Cationic polysaccharides within the therapy of pathogenic Candida infections / Avital Mazar Ben-Josef, David Platt, and Eliezer Zomer --
New ways in synthesis and computational stories. artificial ways to comprise [alpha]-linked 2-amino-2-deoxy-D-glucopyranoside and 2-amino-2-deoxy-D-galactopyranoside residues into glycoconjugate constructions / Robert J. Kerns and Peng Wei --
Systematic synthesis of aminosugars and their stereoselective glycosylation / Jinhua Wang and Cheng-Wei Tom Chang --
functional functions of computational experiences of the glycosylation response / Dennis M. Whitfield and Tomoo Nukada.

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Recent studies also have shown C 7 5 to have significant in vivo antitumor activity against human breast-cancer xenografts (30). Therefore the development o f C 7 5 should enable extensive in-vivo study o f F A S inhibition i n human cancer as w e l l as i n other diseases associated with dysfunctional fatty acid synthesis activity. ; ACS Symposium Series; American Chemical Society: Washington, DC, 2006. ch002 Sulfur as either a sugar heteroatom or a component o f a functional group attached to a strategically important position o f sugar ring ( C - l , C - 6 , or C-4) has the ability to drastically change the chemical character o f a sugar and, consequently, its biological activity.

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1993. Carbohydrates - Synthetic Methods and Application in Medicinal Chemistry, Ogura, H . ; Suami, T. , Kodansha, Tokyo, & V C H Weinheim, 1992. Glyconjugates Composition, Structure and Functions, Allen H . J. , Eds. Marcel Dekker, New York, 1992. Carbohydrate-based drug discovery, Wong C - H . Ed, Wiley-VCH, Weinheim, 2003. Witczak, Z. J. Curr. Med. Chem. 1995, 1, 392. ; Hindsgaul, O. Chem. & Ind. 1997, 170. ; ACS Symposium Series; American Chemical Society: Washington, DC, 2006. 44 10. Yarema, Κ.

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