Cardiac Drug Therapy Khan by M. Gabriel Khan

By M. Gabriel Khan

Cardiac Drug remedy: seventh version updates and revises the 6th version in different respects. the hot variation contains six new chapters that take care of ongoing controversies concerning the use of numerous accepted medications. those chapters comprise the betablocker controversies, ACE inhibitor controversies, calcium antagonist controversies, high blood pressure controversies, middle failure controversies, and Statin controversies.

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Beta-blockers divert blood from the epicardium to the ischemic subendocardium by activation of autoregulatory mechanisms. Calcium antagonists may have the opposite effect and can cause deterioration in patients with critical coronary artery stenosis (41). Unfortunately, calcium antagonists, when used without a beta-blocker in patients with unstable angina, can increase chest pain and infarction, and they appeared to increase mortality in the largest subgroup of patients with unstable angina. Oral nitrates have an effect similar to that of calcium antagonists.

Brophy CM, Tilson JE, Tilson MD. Propranolol stimulates the crosslinking of matrix components in skin from the aneurysm-prone blotchy mouse. J Surg Res 1989;46:330. 61. Boucek RJ, Gunja-Smith Z, Noble NL, et al. Modulation by propranolol of the lysyl cross-links in aortic elastin and collagen of the aneurysm-prone turkey. Biochem Pharmacol 1983;32:275. 62. Handlin LR, Kindred LH, Beauchamp GD, et al. Reversible left ventricular dysfunction after subarachnoid hemorrhage. Am Heart J 1993;126:235.

Circulation 85(Suppl I): 1992;I107. 27. Deanfield J, Wright C, Krikler S. Cigarette smoking and the treatment of angina with propranolol, atenolol and nifedipine. N Engl J Med 1984;310:951. 28. Valimaki ML, Harno K. Lipoprotein lipids and apoproteins during beta-blocker administration: Comparison of penbutolol and atenolol. Eur J Clin Pharmacol 1986;30:17. 29. Pasotti C, Zoppi A, Capra A. Effect of beta-blockers on plasma lipids. Int J Clin Pharmacol Ther Toxicol 1986;24:448. 30. Khan M Gabriel.

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