Coronary Heart Disease in Women: Prevention - Diagnosis - by Elisabeth von der Lohe

By Elisabeth von der Lohe

Take benefit of new insights into prevention, analysis and therapy of heart disorder in girls - to the good thing about your sufferers. Designed to optimize your day-by-day perform, this e-book supplies lucid, updated solutions to varied questions:

- What are the hazards and merits of hormone alternative therapy?

- What are the foremost threat components for heart sickness in women?

- What are the main acceptable diagnostic checks in women?

- that is the higher therapy alternative for the girl with myocardial infarction - lysis or basic angioplasty?

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Coronary Heart Disease in Women: Prevention - Diagnosis - Therapy

Reap the benefits of new insights into prevention, analysis and therapy of heart disorder in ladies - to the good thing about your sufferers. Designed to optimize your day-by-day perform, this booklet supplies lucid, updated solutions to various questions:- What are the dangers and advantages of hormone alternative treatment?

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Extra resources for Coronary Heart Disease in Women: Prevention - Diagnosis - Therapy

Sample text

1991) A prospective study of maturity-onset diabetes mellitus and risk of coronary heart disease and stroke in women. Arch Intern Med 151:1141–1147 Manson JE, Hu FB, Rich-Edwards JW et al. (1999) A prospective study of walking as compared with vigorous exercise in the prevention of coronary heart disease in women. N Engl J Med 341:650 Miller VT (1994) Lipids, lipoproteins women and cardiovascular disease. Artherosclerosis 108:S73 Mosca L, Grundy SM, Judelson D et al. (1999) Guide to preventative cardiology for women.

36 Effects of Estrogen . . . . . . . . . . 38 References . . . . . . . . . . . . 44 E. von der Lohe, Coronary Heart Disease in Women © Springer-Verlag Berlin Heidelberg 2003 36 Chapter 3 · Pathophysiology of Coronary Heart Disease and the Effects of Estrogen Basics Atherosclerosis of the coronary arteries is the underlying pathophysiological mechanism of coronary heart disease (CHD) and is the same for both genders. There are numerous different theories with regard to the genesis of atherosclerosis.

4. Potentially, an anti-arrhythmic effect. It remains to be seen, however, whether the suppression of ischemia-induced cardiac arrhythmias shown in animal experiments has any clinical correlation. Effect of Estrogen on Lipid Metabolism The lipid profile in healthy premenopausal women is cardioprotective: high high-density lipoproteins (HDL); low LDL; and low total cholesterol. With a decrease of endogenous estrogen production (either secondary to natural menopause, chemotherapy, or ovariectomy) a change from a more atherogenic pattern is observed with elevated cholesterol- and LDL levels and relatively low HDL (see also chap.

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